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Can AI systems discover better neural architectures than humans?

Can multi-agent LLM systems, when structured with genetic programming, discover novel neural network designs that outperform human-engineered architectures? This matters because it could automate a critical bottleneck in AI research.

Synthesis note · 2026-02-23 · sourced from Novel Architectures

Genesys models the conventional stages of research — ideation, literature search, code generation, pretraining, evaluation — as a multi-agent LLM system. The key innovation is the Ladder of Scales approach: new designs are proposed, adversarially reviewed, implemented, and selectively verified at increasingly larger model scales (14M→350M parameters) with a narrowing budget at each scale.

The genetic programming (GP) backbone is critical. Rather than using LLMs to directly prompt-generate architectures (which has an ~86% failure rate), Genesys represents architectures as Generalized Autoregressive Blocks (GABs) — a code construct factorizable into discrete tree representations. GP-style operations (crossover, mutation) on these trees produce meaningful architectural variations far more reliably than direct generation.

Results: 1,162 newly discovered designs (1,062 fully verified through pretraining). The best designs outperform GPT-2, Mamba-2, and other known architectures on 6/9 common benchmarks. This is achieved through a principled search process, not brute-force sampling.

The system architecture mirrors human research:

Unlike traditional Neural Architecture Search (NAS) which searches within human-defined operation spaces (attention heads, convolution kernels), Genesys searches a broader space of operations and architectures while modeling the broader scientific discovery process.

The factorization into GP-representable trees is the insight that makes this practical: it provides structure to the search space that direct LLM generation lacks. The ~86% improvement in successful design generation from GP vs. direct prompting suggests that current LLMs need structured representations to do creative design work reliably — they cannot yet reliably generate novel working architectures from freeform description alone.

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How do neural networks achieve compositional generalization at scale? How should designers communicate what AI systems truly are and can do? How can evolutionary algorithms maintain diversity during solution search? How effectively can language models perform reasoning, especially combined with symbolic methods?

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Original note title

multi-agent LLM systems discover novel neural architectures competitive with human-designed ones through genetic programming